Figure 5
Inflammatory cells in BALF of rat lungs after instillation of 1.5 and 0.5 μm Fe 2 O 3 particles ( in vivo study). Healthy WKY rats were intratracheally instilled with 1.5 μm or 0.5 μm Fe2O3 particles, respectively, at a dose of 1.3 mg/kg body weight and 4.0 mg/kg body weight. At 24 h after instillation pulmonary immune cells such as alveolar macrophages (A) and neutrophils (B) were assessed in the BALF of control and exposed rats. The data are given as mean ± SD with (n = 6) representing 6 animals for each dose and type of particles. * P-value (< 0.05) for significant difference between saline control and Fe2O3 particle exposed rats.