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Table 3 Functional analysis of probes that differ according to factor Time.*

From: Toxicogenomic analysis of susceptibility to inhaled urban particulate matter in mice with chronic lung inflammation

Functional term Number of genes % of total P-value
response to biotic stimulus 29 10.28% 3.86 × 10-6
defence response 28 9.93% 5.78 × 10-6
immune response 24 8.51% 2.23 × 10-5
apoptosis 19 6.74% 5.59 × 10-4
intracellular signalling cascade 28 9.93% 5.94 × 10-4
lipid catabolism 7 2.48% 0.001
protein amino acid methylation 4 1.42% 0.004
nitrogen compound catabolism 5 1.77% 0.009
response to stress 22 7.80% 0.009
angiogenesis 7 2.48% 0.01
  1. * DAVID functional annotation analysis http://david.abcc.ncifcrf.gov/home.jsp was carried out using the list of all genes responding according to factor Time (286 probes; 282 unique DAVID IDs), with the Agilent Mouse Microarray G4121A probe list serving as background. Representative terms selected from 50 gene ontology terms with a modified Fisher's Exact p < 0.05 are displayed.