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Table 3 Functional analysis of probes that differ according to factor Time.*

From: Toxicogenomic analysis of susceptibility to inhaled urban particulate matter in mice with chronic lung inflammation

Functional term

Number of genes

% of total

P-value

response to biotic stimulus

29

10.28%

3.86 × 10-6

defence response

28

9.93%

5.78 × 10-6

immune response

24

8.51%

2.23 × 10-5

apoptosis

19

6.74%

5.59 × 10-4

intracellular signalling cascade

28

9.93%

5.94 × 10-4

lipid catabolism

7

2.48%

0.001

protein amino acid methylation

4

1.42%

0.004

nitrogen compound catabolism

5

1.77%

0.009

response to stress

22

7.80%

0.009

angiogenesis

7

2.48%

0.01

  1. * DAVID functional annotation analysis http://david.abcc.ncifcrf.gov/home.jsp was carried out using the list of all genes responding according to factor Time (286 probes; 282 unique DAVID IDs), with the Agilent Mouse Microarray G4121A probe list serving as background. Representative terms selected from 50 gene ontology terms with a modified Fisher's Exact p < 0.05 are displayed.