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Table 1 Basal levels of transcription factor activation, mRNA expression, and protein levels in different regions of the rat brain.

From: Effect of prolonged exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain

Brain Regions Transcription Factor RNA Protein
  NF-κB AP-1 TNF-α TNFRI TNFα IL-1α
OB+T +++ +++ + + +/++ ++
Cortex + + + + + +
Striatum +/++ + + + ++ ++/+++
Hippocampus ++ ++ +/++ + ++ ++/+++
Cerebellum ++/+++ + +/++ + +/++ ++/+++
  1. For comparison purposes, values are designated as (+ = low; ++ = medium; or +++ = high) based on arbitrary assessment between groups for each marker.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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