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Table 5 Hematological values for male rats after 90-day oral administration of silver nanoparticles (mean ± SD)

From: Subchronic oral toxicity of silver nanoparticles

  Dose (mg/Kg)
  0 (n = 9) 30 (n = 9) 125 (n = 10) 500 (n = 10)
WBC 8.33 ± 1.25 8.22 ± 1.44 8.17 ± 1.28 8.21 ± 1.07
RBC 8.98 ± 0.32 9.13 ± 0.66 8.88 ± 0.24 9.07 ± 0.35
Hb 16.67 ± 0.40 16.76 ± 1.10 16.47 ± 0.53 16.93 ± 0.68
HCT 36.96 ± 1.41 37.80 ± 2.90 36.97 ± 1.46 37.84 ± 2.12
MCV 41.17 ± 0.58 41.38 ± 0.72 41.62 ± 0.77 41.72 ± 0.92
MCH 18.58 ± 0.34 18.34 ± 0.40 18.55 ± 0.58 18.67 ± 0.37
MCHC 45.13 ± 1.08 44.38 ± 1.31 44.59 ± 1.69 44.79 ± 1.25
RDW 17.98 ± 0.78 17.83 ± 0.68 17.83 ± 1.04 18.10 ± 0.86
PLT 738.22 ± 53.33 731.56 ± 105.79 725.40 ± 45.43 718.50 ± 72.05
MPV 6.86 ± 0.29 6.84 ± 0.19 6.83 ± 0.27 6.64 ± 0.28
NEU 26.13 ± 3.30 26.72 ± 3.14 26.76 ± 4.14 27.12 ± 2.62
LYO 69.77 ± 3.39 68.21 ± 3.45 68.93 ± 5.30 69.34 ± 3.13
MONO 3.78 ± 0.80 4.57 ± 1.12 3.98 ± 1.19 3.35 ± 0.80
EOS 0.25 ± 0.40 0.39 ± 0.50 0.25 ± 0.21 0.15 ± 0.08
BASO 0.08 ± 0.14 0.12 ± 0.22 0.09 ± 0.08 0.04 ± 0.03
  1. Note. WBC(K/μL), White blood cells; RBC(M/μL), Red blood cells; Hb(g/dL), Hemoglobin; HCT(%), Hematocrits; MCV(fl), Mean corpuscular volume; MCH(pg), Mean corpuscular hemoglobin; MCHC(g/dL), Mean corpuscular hemoglobin concentration; RDW(%), Red cell distribution width; PLT(K/μL), Platelets; MPV(fl), Mean platelet volume; NEU(%), Neutrophils; LYO(%), Lymphocytes; MONO(%), Monocytes; EOS(%), Eosinophils; BASO(%), Basophils.