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Table 5 Hematological values for male rats after 90-day oral administration of silver nanoparticles (mean ± SD)

From: Subchronic oral toxicity of silver nanoparticles

 

Dose (mg/Kg)

 

0 (n = 9)

30 (n = 9)

125 (n = 10)

500 (n = 10)

WBC

8.33 ± 1.25

8.22 ± 1.44

8.17 ± 1.28

8.21 ± 1.07

RBC

8.98 ± 0.32

9.13 ± 0.66

8.88 ± 0.24

9.07 ± 0.35

Hb

16.67 ± 0.40

16.76 ± 1.10

16.47 ± 0.53

16.93 ± 0.68

HCT

36.96 ± 1.41

37.80 ± 2.90

36.97 ± 1.46

37.84 ± 2.12

MCV

41.17 ± 0.58

41.38 ± 0.72

41.62 ± 0.77

41.72 ± 0.92

MCH

18.58 ± 0.34

18.34 ± 0.40

18.55 ± 0.58

18.67 ± 0.37

MCHC

45.13 ± 1.08

44.38 ± 1.31

44.59 ± 1.69

44.79 ± 1.25

RDW

17.98 ± 0.78

17.83 ± 0.68

17.83 ± 1.04

18.10 ± 0.86

PLT

738.22 ± 53.33

731.56 ± 105.79

725.40 ± 45.43

718.50 ± 72.05

MPV

6.86 ± 0.29

6.84 ± 0.19

6.83 ± 0.27

6.64 ± 0.28

NEU

26.13 ± 3.30

26.72 ± 3.14

26.76 ± 4.14

27.12 ± 2.62

LYO

69.77 ± 3.39

68.21 ± 3.45

68.93 ± 5.30

69.34 ± 3.13

MONO

3.78 ± 0.80

4.57 ± 1.12

3.98 ± 1.19

3.35 ± 0.80

EOS

0.25 ± 0.40

0.39 ± 0.50

0.25 ± 0.21

0.15 ± 0.08

BASO

0.08 ± 0.14

0.12 ± 0.22

0.09 ± 0.08

0.04 ± 0.03

  1. Note. WBC(K/μL), White blood cells; RBC(M/μL), Red blood cells; Hb(g/dL), Hemoglobin; HCT(%), Hematocrits; MCV(fl), Mean corpuscular volume; MCH(pg), Mean corpuscular hemoglobin; MCHC(g/dL), Mean corpuscular hemoglobin concentration; RDW(%), Red cell distribution width; PLT(K/μL), Platelets; MPV(fl), Mean platelet volume; NEU(%), Neutrophils; LYO(%), Lymphocytes; MONO(%), Monocytes; EOS(%), Eosinophils; BASO(%), Basophils.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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