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Table 3 Endobronchial biopsy concentrations of antioxidants, antioxidant enzyme and protein

From: Antioxidant airway responses following experimental exposure to wood smoke in man

 

Air

Wood smoke

Reduced GSH (μM/mg protein)

25.9 (19.3 - 29.3)

22.8 (20.2 - 27.5)

% GSSG

7.4 (4.5-9.9)

9.0 (6.6-15.8)

Ascorbate (μM/mg protein)

8.07 (6.35 - 10.1)

8.02 (6.67 - 10.2)

% DHA

23.1 (17.5-32.9)

23.0 (15.4-33.0)

Urate (μM/mg protein)

1.59 (1.09 - 2.24)

1.80 (0.11 - 2.85)

HO-1 (ng/mg protein)

7.32 (4.48 - 9.95)

7.52 (5.34 - 9.89)

Total Protein (mg/ml)

0.12 (0.09 - 0.16)

0.12 (0.10 - 0.14)

Glutathione S-transferase (U/mg protein)

0.55 (0.39 - 0.82)

0.59 (0.37 - 0.84)

  1. Antioxidant and protein concentrations as well as glutathione S-transferase activity in endobronchial biopsies obtained from subjects exposed to wood smoke (mean 224 μg/m3 PM2.5 for 3 hours) and filtered air. No significant differences between air and wood smoke were detected. Data are given as medians with inter-quartile ranges.