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Table 2 The EC50 values of different Si NP obtained from experiments reported in this article

From: Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells

Assay

Parameter

Reference figure

Si NP-NH2

Si NP-N3

MTT

Mitochondrial metabolic activity

Figure 1

12

270

Phagocytosis Index

Induction Factor

Figure 2

60

320

DCFH-DA

Intracellular ROS production

Figure 3A (NR8383)

22

170

  

Figure 3B (Caco-2)

18

310

DCFH-DA

ROS production (from isolated mitochondrial fraction)

Figure 4

80

1050

MTT (in presence of antioxidants vitamin E and

vitamin C)

Mitochondrial metabolic activity

Figure 5 (for Vitamin E)

60

310

  

Figure 5 (for Vitamin C)

32

510