Bradykinin, RMP-7
|
Transient increase of permeability, activates B2 receptors
|
[116]
|
VEGF, HIF-1, Deferoxamine,
|
Increase of permeability and leakage
|
[117, 118]
|
TNF-alpha, IL-1beta
|
Moderate increase of permeability
|
[119]
|
Tat, Nef, gp120 + IFN-gamma
|
HIV-1-associated dysfunction
|
[28–30, 120, 121]
|
Low magnetic field (0.15 T)
|
Moderated increase of permeability
|
[122, 123]
|
Metalloproteinases
|
Increase of permeability
|
[124]
|
LTC4
|
Leukotriene-induced permeability
|
[125, 126]
|
Lipopolysaccharide
|
Enhance the passage of regulatory proteins
|
[127, 128]
|
P85
|
Increase permeability by inhibiting the drug efflux transporter Pgp
|
[129]
|
endothelin-1
|
Dramatic increase of permeability after intracisternal administration
|
[130]
|
tPA
|
Increase permeability via Akt phosphorylation
|
[131]
|
PTX
|
Increased permeability by altering endothelial plasticity and angiogenesis
|
[132]
|