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Figure 5 | Particle and Fibre Toxicology

Figure 5

From: Inhalation exposure to nanosized and fine TiO2 particles inhibits features of allergic asthma in a murine model

Figure 5

Airway responsiveness to metacholine. Effect of airway responsiveness to metacholine (MCh) in allergic mice after exposure to nanosized (A; nTiO2) or fine (B; fTiO2) TiO2 for 2 hours a day, three days a week, for four weeks at a concentration of 10 mg/m3 (n = 8 mice per group). Results are shown as enhanced pause (Penh) values, dimensionless values that we used to empirically monitor airway function, in relation to increasing doses (1-100 mg/ml) of aerosolized MCh for healthy (PBS) and allergic (OVA) mice.

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