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Table 2 Long-term dissolution parameters (mean ± standard deviation) for tungsten-containing materials after immersion in artificial airway epithelial lining fluid (pH 7.4) for 72 hours

From: Persistence of tungsten oxide particle/fiber mixtures in artificial human lung fluids

 

As Received

Dispersed

Mixture with Cobalt

Powder

t 1/2 (days)

k [g/(cm 2 ·day)]

t 1/2 (days)

k [g/(cm 2 day)]

t 1/2 (days)

k [g/(cm 2 ·day)]

WO3

4 ± 1

2.5 ± 0.3 × 10-5

11a

0.9 × 10-5

79 ± 23

1.3 ± 0.4 × 10-6

WO2.98

1 ± 0

6.0 ± 1.2 × 10-6

1 ± 0

6.0 ± 2.3 × 10-6

10 ± 2

6.5 ± 1.6 × 10-7

WO2.81

11 ± 2

2.3 ± 0.3 × 10-6

13 ± 1

1.9 ± 0.1 × 10-6

71 ± 6

3.5 ± 0.3 × 10-7

WO2.66b

56 ± 10

8.4 ± 1.7 × 10-7

41 ± 2

1.1 ± 0.1 × 10-6

72 ± 22

6.8 ± 1.8 × 10-7

WO2.51

81 ± 4

4.1 ± 0.2 × 10-7

50 ± 14

6.9 ± 1.7 × 10-7

89 ± 13

3.8 ± 0.6 × 10-7

W

19 ± 2

5.4 ± 0.5 × 10-6

--c

--

--

--

  1. a Result for WO3 in dispersed state is for n = 1 sample
  2. b Values for t1/2 (days) and k [g/(cm2·day)] calculated using surface-area-limited dissolution model: 30 ± 6, 1.6 ± 0.3 × 10-6 (as-received); 22 ± 2, 2.1 ± 0.2 × 10-6 (dispersed); 37 ± 11, 1.3 ± 0.3 × 10-6 (mixture).
  3. c Not applicable for the tungsten metal samples