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Table 3 Dopamine turnover in each part of the brain.

From: In utero exposure to a low concentration of diesel exhaust affects spontaneous locomotor activity and monoaminergic system in male mice

Brain region

Group

Turnover

  

DOPAC/dopamine

3-MT/dopamine

HVA/dopamine

(DOPAC+HVA)/dopamine

Striatum

Control

0.076 ± 0.004

0.077 ± 0.004

0.121 ± 0.004

0.197 ± 0.006

 

Exposed

0.064 ± 0.002*

0.071 ± 0.003

0.098 ± 0.004*

0.162 ± 0.005**

Hippocampus

Control

--

0.60 ± 0.14

24.66 ± 12.22

--

 

Exposed

--

0.51 ± 0.06

5.15 ± 0.64

--

Midbrain

Control

0.61 ± 0.05

0.20 ± 0.03

0.99 ± 0.13

1.601 ± 0.165

 

Exposed

0.55 ± 0.03

0.17 ± 0.01

0.86 ± 0.06

1.404 ± 0.079

Cerebellum

Control

--

--

17.22 ± 5.55

--

 

Exposed

--

--

39.49 ± 13.83

--

Brainstem

Control

3.22 ± 0.13

--

0.16 ± 0.01

3.38 ± 0.13

 

Exposed

3.25 ± 0.09

--

0.35 ± 0.04

3.60 ± 0.07

  1. Data are presented as mean ± SEM (n = 10 per group). The statistical significance is shown as *P < 0.05, **P < 0.01; ND, not detectable. Abbreviations: DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid; 3-MT, 3-methoxytyramine.