Particle and Fibre Toxicology

Table 4 Noradrenaline turnover in each part of the brain.

From: In utero exposure to a low concentration of diesel exhaust affects spontaneous locomotor activity and monoaminergic system in male mice

Brain region	Group	Turnover
		NM/noradrenaline	MHPG/noradrenaline
Striatum	Control	--	20.62 ± 3.14
	Exposed	--	14.44 ± 2.15
Hippocampus	Control	0.069 ± 0.006	4.59 ± 0.35
	Exposed	0.074 ± 0.007	2.97 ± 0.24**
Midbrain	Control	0.034 ± 0.002	1.84 ± 0.11
	Exposed	0.028 ± 0.003	1.12 ± 0.06**
Cerebellum	Control	0.145 ± 0.011	10.82 ± 1.30
	Exposed	0.131 ± 0.013	6.87 ± 0.36*
Brainstem	Control	0.0568 ± 0.003	0.415 ± 0.015
	Exposed	0.0487 ± 0.003	0.380 ± 0.030

Data are presented as mean ± SEM (n = 10 per group). The statistical significance is shown as *P < 0.05, **P < 0.01; ND, not detectable. Abbreviations: MHPG, 4-hydroxy-3-methoxyphenylglycol; NM, normetanephrine.

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ISSN: 1743-8977

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