Figure 4

The chemokines KC and MCP-1 are elevated in A/J and BALB mice following V ₂ O ₅ treatment. A.) KC, keratinocyte chemoattractant, B.) MIP-2, macrophage inflammatory protein-2, C.) MCP-1, monocyte chemoattractant protein-1 levels were determined in lung homogenates (25-50 μg protein) by ELISA. Values are presented as means ± SEM from two independent assays. *, significantly different than strain-matched PBS controls. †, significantly different than time-matched B6 mice. δ, significantly different than time-matched BALB mice. **, significant treatment effect (6 hr V₂O₅ vs PBS control). ‡, significant strain effect (A/J vs B6, BALB vs B6). #, significant strain effect (A/J vs BALB) (P < 0.05).