Figure 6
From: Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner
ERK1/2 is differentially activated in A/J compared to B6 mice following sub-chronic V 2 O 5 instillation. Homogenates were prepared from the right lungs of mice A.) 6 hr and B.) 1 day after the last V2O5 exposure (n = 3-5/group). Phosphorylated and total levels of MAPK in lung homogenates were analyzed from 100 μg protein by Western blotting. Representative images and mean band intensities are representative of 2-3 independent experiments. *, significantly different than strain-matched PBS controls (P < 0.05). **, significant main effect of time. †, significantly different than time-matched B6 mice (P < 0.05).