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Figure 7 | Particle and Fibre Toxicology

Figure 7

From: Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs

Figure 7

Proteomic analysis of DCB230 exposed neonatal lungs. (A) 2-D gel proteomic map with selected spots indicating a significant intensity change vs air exposed controls. (B) Enlargement of panels 4 and 5 from air and DCB230 exposed lungs. Panel 4 indicates PRDX6 expression (1.33 increase, p < 0.00034) and panel 5 indicates CFL1 expression (1.34 increase, p < 0.0008). (C) Western blot confirmation of increased expression of both proteins following exposure to DCB230 as compared to air or DCB50. n = 4-6 animals/group.

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