Fibrotic plaques on the peritoneal face of the diaphragm following intraperitoneal instillation of CNT
and LFA fibres. A. Differential development of fibrotic plaques on the peritoneal face of the diaphragm following the injection of CNTLONG1 or LFA fibres that had been incubated for 0 weeks (left panels) or 10 weeks (right panels). Black rods indicate the depth of the fibrotic plaque and show that 10 weeks incubation in Gambles solution did not impact the response to LFA fibres, whereas the fibrotic response from CNTLONG1 0 weeks was largely absent in mice injected with CNTLONG1 10 weeks. Co-localisation of fibrotic plaques with CNTLONG1 fibres (B) or LFA fibres (C) (indicated by black chevrons) is also shown.