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Table 4 Summary of results from experiments to determine durability, and acute and 7 d inflammatory responses in vivo, for CNT samples and controls

From: Durability and inflammogenic impact of carbon nanotubes compared with asbestos fibres

   Fibre Changes Acute Inflammatory Response (24 h) 7 d Inflammatory Response
   Loss of Mass Fibre Shortening Total Cell PMN Infiltration Total Protein IL-6 LDH Total Cell PMN Infiltration Total Protein IL-6 LDH Granuloma Response
X607 0 week N/A N/A - - - - - - - - - - -
  10 week + + - - - - - - - - - - -
LFA 0 week N/A N/A + + - - - - - - - - Yes (ns)
  10 week + - + + - - - - - - - - Yes (ns)
LFC 0 week N/A N/A + + + - - - - - - - Yes (ns)
  10 week + + - - - - - - - - - - -
CNT SW 0 week N/A N/A - - - - - - - - - - -
  10 week - - - - - - - - - - - - -
CNT LONG1 0 week N/A N/A + + + + - - - + + + Yes (s)
  10 week +* + - - - - - - - - - - -
  1. This table compiles and summarises data presented in Tables 2 and 3, and Figures 1, 2, 3 and 5. A cross indicates a statistically significant difference between treatment and control (for fibre changes, 10 weeks compared with 0 weeks; for inflammatory responses, response to fibre sample compared with vehicle only). A dash indicates no statistically significant difference.
  2. (+ = statistically significant (p < 0.05); - = not statistically significant; (ns) = not significant; (s) = significant; N/A: not applicable)
  3. * Note: The mass loss for CNTLONG1 10 weeks was just under statistical significance; however the mass losses at 3 weeks, 6 weeks and 24 weeks were significant, and therefore representative statistical significance has been attributed to the 10 week sample here.