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Table 9 Gold distribution in tissue of female rats after 90-day gold nanoparticle exposure.

From: Subchronic inhalation toxicity of gold nanoparticles

GROUP: (mean ± S.E)

Control

Low

Middle

High

Lungs (ng/g)

13.75 ± 0.95 (5)

15.07 ± 2.02 (5)

28.34 ± 1.16 (5)

1960.02 ± 92.80a (5)

Liver (ng/g)

16.57 ± 3.89 (5)

12.08 ± 2.13 (5)

12.31 ± 1.18 (5)

14.96 ± 1.54 (5)

Kidneys (ng/g)

21.27 ± 0.65 (5)

19.43 ± 0.79 (5)

26.37 ± 0.79 (5)

61.90 ± 3.15a,** (5)

Brain (ng/g)

19.13 ± 2.31 (5)

18.42 ± 1.07 (5)

17.87 ± 0.86 (5)

22.15 ± 0.75** (5)

Olfactory bulb (ng/g)

23.19 ± 2.45 (10)

20.22 ± 4.35 (10)

23.56 ± 4.15 (10)

22.92 ± 4.07 (10)

Blood (ng/ml)

6.66 ± 0.78 (10)

6.92 ± 1.08 (10)

5.10 ± 0.58 (10)

8.98 ± 1.25 (10)

  1. ( ), number of animals; a, p < 0.01 high group vs. other groups; **, p < 0.01 female rats vs. male rats in high group