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Table 9 Gold distribution in tissue of female rats after 90-day gold nanoparticle exposure.

From: Subchronic inhalation toxicity of gold nanoparticles

GROUP: (mean ± S.E) Control Low Middle High
Lungs (ng/g) 13.75 ± 0.95 (5) 15.07 ± 2.02 (5) 28.34 ± 1.16 (5) 1960.02 ± 92.80a (5)
Liver (ng/g) 16.57 ± 3.89 (5) 12.08 ± 2.13 (5) 12.31 ± 1.18 (5) 14.96 ± 1.54 (5)
Kidneys (ng/g) 21.27 ± 0.65 (5) 19.43 ± 0.79 (5) 26.37 ± 0.79 (5) 61.90 ± 3.15a,** (5)
Brain (ng/g) 19.13 ± 2.31 (5) 18.42 ± 1.07 (5) 17.87 ± 0.86 (5) 22.15 ± 0.75** (5)
Olfactory bulb (ng/g) 23.19 ± 2.45 (10) 20.22 ± 4.35 (10) 23.56 ± 4.15 (10) 22.92 ± 4.07 (10)
Blood (ng/ml) 6.66 ± 0.78 (10) 6.92 ± 1.08 (10) 5.10 ± 0.58 (10) 8.98 ± 1.25 (10)
  1. ( ), number of animals; a, p < 0.01 high group vs. other groups; **, p < 0.01 female rats vs. male rats in high group