Skip to main content

Table 1 Sensitivity of Interstitial Fibrotic Response to SWCNTs versus MWCNTs

From: Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes

 

SWCNTs1

MWCNTs

Aspiration Dose

(ug)

10 ug

80 ug

Lung Burden Distribution

(%)

10% Alveolar Macrophage

90% Interstitial

70% Alveolar Macrophage

8% Interstitial

20% Airspace Granuloma

2% Subpleural Tissue

Alveolar Interstitial Dose

(ug)

9 ug

6.4 ug

Connective Tissue Thickness (um)

0.10 to 1.10

Control Exposed

0.11 to 0.19

Control Exposed

Sensitivity

Δum Thickness/Δug Dose

0.11 um/ug

0.013 um/ug

  1. 1 Data for dispersed SWCNT interstitial response from Mercer et al. [3]