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Table 5 Inflammatory markers measured in mice exposed to nTiO2 (0.5 mg/kg) or control bronchoalveolar lavage (BAL) suspension by intratracheal instillation once a week for four weeks and sacrificed 5 weeks later (n = 10).

From: Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO2

Exposure i.t. instillation mRNA expression level (Median (quartile 25-75%))
  Mcp-1 (*10 -9 ) Mip-2 (*10 -9 ) Icam-1 (*10 -6 ) Vcam-1 (*10 -6 ) Vegf (*10 -6 )
Control 141.9 (98.3-166.5) 43.2 (39.3-53.0) 21.8 (17.4-39.0) 0.30 (0.13-0.50) 0.70 (0.45-1.18)
nTiO2 265.9 (80.6-359.5) 53.3 (25.4-140.2) 38.9 (18.6-56.9) 0.40 (0.23-0.83) 0.90 (0.78-1.38)
  1. Expression of mRNA is normalised to 18S rRNA.