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Figure 3 | Particle and Fibre Toxicology

Figure 3

From: Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures

Figure 3

The release of inflammatory mediators was measured after aSNP (Ludox TM-40: light grey, NexSil20: dark grey) exposure of monocultures of H441 and ISO-HAS-1 on 96 well plates (conventional monoculture). After 4 h incubation, aSNPs were removed and the cells were cultivated for further 20 h to detect sICAM-1, IL-6 and IL-8 release. Data are depicted as means ± S.D. of one representative experiment out of three independent experiments with n = 3 samples for each treatment. All independent experiments showed a comparable reaction following aSNP treatment. *P < 0.05, ** P < 0.01 and *** P < 0.001 compared to the untreated control

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