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Figure 5 | Particle and Fibre Toxicology

Figure 5

From: Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos

Figure 5

Biomarkers of oxidative stress in the lung of C57BL/6 Mice following aspiration with CNF, Crocidolite Asbestos, or SWCNT. A: 4-Hydroxynonenal; B: Protein Carbonyl. Mice were exposed via pharyngeal aspiration to the doses indicated. Open columns - exposure with SWCNT (40 μg/mouse); gray columns - exposure with CNF (120 μg/mouse); black columns - exposure with crocidolite asbestos (120 μg/mouse). Animals were sacrificed 1, 7, and 28 days post exposure. Means ± SE (n = 6 mice per group). *p < 0.05 vs. control (PBS) exposed mice; αp < 0.05 vs. CNF exposed mice; βp < 0.05 vs. asbestos exposed mice.

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