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Figure 4 | Particle and Fibre Toxicology

Figure 4

From: Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro

Figure 4

Endpoints measured in triple cell co-cultures. Triple cell co-cultures consisting of MDM, MDDCs and 16HBE14o cells were exposed to different functionalized and pre-coated MWCNTs. Endpoints were assessed after 24 h exposures. a. Cytotoxicity (lactate dehydrogenase release), b. Intracellular glutathione, c. Tumour necrosis factor-α (for an optimized representation of group comparisons the same data are visualized in two diagrams. Values are shown relative to the medium control which corresponds to a mean concentration of 249 pg/ml for the upper well and 201 pg/ml for the lower well), d. Interleukin-8 (values are shown relative to the medium control which corresponds to a mean concentration of 1.39 ng/ml for the upper well and 1.37 ng/ml for the lower well). Experiments have been performed in 5 repetitions. Bars represent mean values ± SD. Different groups were compared by ANOVA and Bonferroni post hoc tests (* = p < 0.05).

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