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Figure 5 | Particle and Fibre Toxicology

Figure 5

From: Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

Figure 5

Transmission electron micrographs detailing autophagic vacuoles. Porcine kidney cells (LLC-PK1) were treated for 24 h with either (A) 10 nM CdSe or (B) 100 nM InGaP quantum dots. The white arrows indicate autophagic vacuoles containing cellular debris. The black arrows indicate lysosomal remnants, consisting of multilamellar vacuoles and electron-dense deposits. (Stern ST, et al, Induction of Autophagy in Porcine Kidney Cells by Quantum Dots: A Common Cellular Response to Nanomaterials? Tox. Sci. 2008, 106(1), 140–152, by permission of Oxford University Press.)

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