Figure 2
From: Type I interferon and pattern recognition receptor signaling following particulate matter inhalation
Top molecular network in whole blood cells 28 d after GMA-SS inhalation exposure. Gene network analysis by IPA indicated a significant type I interferon response following exposure. The network contained 25 of 35 focus molecules with a score of 44. A score of 44 means there is a 1 in 1044 chance of this network occurring by random chance. Intensity of the red (upregulated) or green (downregulated) color indicates level of gene expression. The white color indicates a predicted molecule incorporated from the Ingenuity knowledge base. Gray represents a molecule present in the dataset, but one that did not meet the specified cutoff criteria.