Figure 5
From: Type I interferon and pattern recognition receptor signaling following particulate matter inhalation
A top molecular network in lung at 28 d after GMA-SS inhalation exposure. Gene network analysis by IPA indicated a significant type I interferon response following exposure. The network contained 22 of 35 focus molecules with a score of 30. A score of 30 means there is a 1 in 1030 chance of this network occurring by random chance. Intensity of the red (upregulated) or green (downregulated) color indicates level of gene expression. The white color indicates a predicted molecule incorporated from the Ingenuity knowledge base. Gray represents a molecule present in the dataset, but one that did not meet the specified cutoff criteria.