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Figure 5 | Particle and Fibre Toxicology

Figure 5

From: Ultrafine particles affect the balance of endogenous pro- and anti-inflammatory lipid mediators in the lung: in-vitro and in-vivo studies

Figure 5

In-vitro study: Effect of UfCP on the generation of endogenous lipid mediator in primary rat alveolar macrophages. Rat AM were incubated with UfCP (10 μg/1x106 cells/ml) for 60 min (UfCP group). Control cells were incubated in parallel without particles. After incubation, the cells were immediately homogenised. The cell lysates were used for determination of the endogenous levels of pro-inflammatory (upper panel), and of anti-inflammatory (lower panel) lipid mediators. The data are given as absolute values (mean ± SD) with n as number of experiments (n = 4-6). *p <0.05 and **p <0.01 vs control.

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