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Figure 1 | Particle and Fibre Toxicology

Figure 1

From: An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

Figure 1

Effects of NM exposure on reduced GSH and total glutathione levels in C3A cells. The cells were exposed to cell medium (control), and increasing concentrations of selected NMs for 24 hr. Values represent mean ± SEM (n = 3), significance indicated by * = p < 0.05 and ** = p < 0.005 compared to the control. A) NM 101 B) NM 110 C) NM 111 D) NM 300 E) NM 400 F) NM 402 G) NRCWE 001 H) NRCWE 002 I) NRCWE 003 J) NRCWE 004. LC50 values are indicated for NMs where this value was measurable. For all other NMs the LC50 was not reached following exposure up to 80 μg/cm2 after 24 hr of incubation.

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