Table 2 Summary of the observed effects on C3A hepatocytes following exposure to the ENPRA panel of nanomaterials
NM | LC50 (WST-1) | GSH Depletion | Increase in intracellular ROS levels | DNA damage |
|---|---|---|---|---|
NM 101 | > 80 μg/cm2 | No | Large | Yes |
NM 110 | 5 - 10 μg/cm2 | Yes | None | Yes |
NM 111 | 10 - 20 μg/cm2 | Yes | Small | Yes |
NM 300 | 1.25 - 2.5 μg/cm2 | Yes | None | Yes |
NM 400 | > 80 μg/cm2 | Yes | Large | Yes |
NM 402 | > 80 μg/cm2 | Yes | Large | Yes |
NRCWE 001 | > 80 μg/cm2 | No | Large | Yes |
NRCWE 002 | > 80 μg/cm2 | No | Large | Yes |
NRCWE 003 | > 80 μg/cm2 | No | Large | No |
NRCWE 004 | > 80 μg/cm2 | No | Large | Yes |