Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection

Table 1 Summary of the physicochemical properties of amorphous silica particles (SPs).

	Primary particle size (nm) ^a	Diameter in PBS (nm)	Mean zeta potential (mV)	pH
mSP1000	1000	1136 ± 32.1	-33.2 ± 1.4	7.6
nSP300	300	264 ± 7.2	-25.8 ± 0.7	7.4
nSP100	100	106 ± 0.6	-24.3 ± 0.5	7.4
nSP70	70	76 ± 1.7	-19.5 ± 1.0	7.4
nSP30	30	39 ± 4.2	-14.0 ± 1.3	7.4

Mean particle size and zeta potential in solution of silica particles are expressed as mean ± S.D. (n = 3). ^a Information from technical datasheet of products.

ISSN: 1743-8977