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Table 1 Subject demographics, pulmonary function data and breathing parameters (Mean ± SD)

From: Experimental determination of the respiratory tract deposition of diesel combustion particles in patients with chronic obstructive pulmonary disease

  Healthy (n = 7) COPD (n = 10)
   % predicted   % predicted
Age (yrs) 30 ± 8   67 ± 7  
Gender 2 M/5 F   7 M/3 F  
Height (cm) 168 ± 9   171 ± 7  
Weight (kg) 63 ± 5   73 ± 10*  
Pack years 0   44 ± 19  
FEV1 (L) 3.71 ± 0.96 107 ± 12 1.80 ± 0.45 66 ± 16
FEV1/FVC 0.79 ± 0.04 95 ± 4 0.49 ± 0.08 65 ± 10
FVC (L) 4.44 ± 1.09 110 ± 10 2.85 ± 0.63 81 ± 18
VC (L) 4.69 ± 1.21 115 ± 14 3.69 ± 0.77 102 ± 22*
TLC (L) 6.13 ± 1.31 109 ± 11 6.9 ± 0.9 112 ± 12
RV (L) 1.40 ± 0.20   3.24 ± 0.58  
RV/TLC 0.24 ± 0.04   0.47 ± 0.08  
PEF (L/s) 8.15 ± 1.66 105 ± 7 5.51 ± 1.70 75 ± 20
MEF50 (L/s) 4.02 ± 1.14 85 ± 21 0.78 ± 0.33 20 ± 8
MEF25 (L/s) 1.56 ± 0.54   0.17 ± 0.06  
DLCO(SB)a 8.46 ± 1.99 92 ± 13 5.14 ±0.64 62 ± 12
DLCO/VA a 1.65 ± 0.06 92 ± 3 0.96 ± 0.19 70 ± 11
MV (L/min) 8.4 ± 1.5   10.6 ± 2.9  
f (breaths/min) 10.7 ± 3.6   13.1 ± 3.4  
VT (L) 0.86 ± 0.26   0.86 ± 0.28  
  1. Abbreviations: MEF25/50 = maximum expiratory flow rate at 25% and 50% of VC respectively, DLCO(SB) = single-breath diffusion capacity for CO [mmol/min/kPa], DLCO/VA = diffusion capacity normalized to lung volume [mmol/min/kPa/L], MV = minute ventilation, f = breathing frequency, VT = tidal volume.
  2. *p < 0.05, p < 0.01, p < 0.001.
  3. a n = 5 for healthy subjects.