Figure 3

Uptake of particles by HUVECs and THP-1 cells. TEM micrographs of cells exposed for 24 h to particles. A) and a): THP-1 cells without any treatment; B) and b): THP-1 cells treated with FeNPs; C) and c) THP-1 cells treated with SiNPs; D) and d): HUVECs without any treatment; E) and e): HUVECs treated with FeNPs; F) and f): HUVECs treated with SiNPs; (A-F): Overall cell morphology (scale bar: 2 μm). (a-f): Higher magnification of part of the area in the cells (scale bar: 1 μm). (N: nucleus, mi: mitochondria). Black arrows denote NPs. Red arrows indicate the protrusion of the plasma membrane for phagocytosis. ( FeNPs: Fe3O4 particles; SiNPs: SiO2 particles).