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Table 2 BAL fluid counts in mice.

From: Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint

   Control   NanoTiO2    Indoor-R    Indoor-NanoTiO2  
1 day    18 μg 54 μg 162 μg 54 μg 162 μg 486 μg 54 μg 162 μg 486 μg
  Neutrophils (x103) 7.7 ± 1.7 4.9 ± 1.5 56.8 ± 7.2*** 189.9 ± 29.1*** 14.2 ± 3.5 61.7 ± 17.8** 176.5 ± 18.8*** 19.7 ± 3.5 58.2 ± 10.5** 170.4 ± 25.3***
  Macrophages (x103) 53.2 ± 2.5 64.1 ± 6.9 56.4 ± 5.8 41.4 ± 6.2 61.1 ± 7.7 69.5 ± 4.1 78.9 ± 13.1 73.0 ± 7.1 68.8 ± 6.6 51.4 ± 7.2
  Eosinophils (x103) 0.3 ± 0.4 0.3 ± 0.2 1.3 ± 0.7 2.1 ± 0.6 0.2 ± 0.1 2.0 ± 1.0 20.5 ± 3.1*** 0.2 ± 0.2 1.3 ± 0.5 10.1 ± 5.4***
  Lymphocytes (x103) 1.6 ± 0.2 1.2 ± 0.5 1.0 ± 0.3 2.4 ± 1.0 0.7 ± 0.2 2.1 ± 0.8 3.4 ± 1.4 0.9 ± 0.2 2.2 ± 0.8 2.7 ± 1.0
  Total BAL cells (x103) 74.0 ± 3.6 77.6 ± 8.8 123 ± 12.8** 246.5 ± 31.1*** 85.4 ± 8.2 146.4 ± 22.1*** 298.8 ± 25.5*** 106.3 ± 9.5 139.2 ± 14.2*** 256.3 ± 29.5***
3days            
  Neutrophils (x103) 3.0 ± 2.3 0.9 ± 0.5 6.5 ± 1.0** 78.1 ± 10.5*** 2.6 ± 1.9 4.4 ± 1.6 17.4 ± 2.7*** 1.5 ± 0.5 3.7 ± 0.9 21.4 ± 5.3***
  Macrophages (x103) 56.4 ± 4.2 58.9 ± 8.5 57.3 ± 6.9 84.2 ± 0.8 56.5 ± 6.2 69.7 ± 6.3 128.9 ± 8.2*** 69.2 ± 7.9 85.6 ± 5.6* 106.6 ± 6.8***
  Eosinophils (x103) 0.4 ± 0.6 0.5 ± 0.2 0.9 ± 0.3 9.7 ± 6.5 4.8 ± 0.4 8.4 ± 2.2*** 45.0 ± 8.3*** 0.9 ± 0.3 7.9 ± 3.8*** 19.0 ± 7.5***
  Lymphocytes (x103) 0.9 ± 0.2 0.8 ± 0.3 0.8 ± 0.2 4.6 ± 1.8 1.5 ± 0.7 6.7 ± 1.6*** 14.1 ± 4.4*** 1.3 ± 0.3 2.9 ± 1.3 8.5 ± 3.4*
  Total BAL cells (x103) 69.1 ± 6.4 66.9 ± 8.6 71.8 ± 8.3 185.3 ± 14.0*** 69.3 ± 6.6 99.4 ± 7.6 221.4 ± 17.2*** 81.0 ± 8.2 109.3 ± 4.8*** 174.9 ± 19.4***
28 days           
  Neutrophils (x103) 1.2 ± 0.2 1.1 ± 0.3 2.8 ± 0.6 14.7 ± 2.7*** 0.6 ± 0.4 1.2 ± 0.4 1.4 ± 0.2 1.1 ± 0.4 1.8 ± 0.9 6.6 ± 2.0
  Macrophages (x103) 82.4 ± 5.7 79.5 ± 5.4 71.8 ± 10.7 106.2 ± 14.6 54.1 ± 3.6 64.0 ± 3.6 91.2 ± 13.3 94.6 ± 23.5 92.8 ± 6.1 141.5 ± 30.4
  Eosinophils (x103) 0.3 ± 0.0 0.5 ± 0.5 1.6 ± 0.0 1.2 ± 1.1 0.0 ± 0.0 1.9 ± 1.5 0.1 ± 0.1 0.07 ± 0.07 0.7 ± 0.6 3.2 ± 2.9
  Lymphocytes (x103) 2.1 ± 0.4 2.0 ± 0.4 3.8 ± 1.0 18.4 ± 3.8 1.4 ± 0.4 2.8 ± 0.6 5.0 ± 1.3 2.0 ± 1.0 1.6 ± 0.5 5.8 ± 2.4
  Total BAL cells (x103) 95.9 ± 5.8 94.1 ± 6.9 85.8 ± 11.6 154.7 ± 16.0* 62.5 ± 3.9 79.5 ± 4.9 108.8 ± 13.0 104.6 ± 25.0* 107.9 ± 6.0 173.6 ± 28.6**#
  1. BAL fluid counts in mice. 1, 3 and 28 days post-exposure to 18 μg, 54 μg and 162 μg NanoTiO2, 54 μg, 162 μg and 486 μg sanding dusts and control mice. *, **, ***: Statistically significant compared to control mice at the 0.5, 0.01 and 0.001 level, respectively. #: Statistically significant difference between the two paints at the 0.05 level