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Figure 8 | Particle and Fibre Toxicology

Figure 8

From: Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model

Figure 8

Alteration of brown adipocyte-specific gene expression in iBAT in response to CAPs, Ni, or CAPs+Ni exposure . N = 5–6. * P < 0.05 vs. FA group; ** P < 0.001 vs. FA group; † P < 0.05 vs. CAPs group; ‡ P < 0.001 vs. CAPs group. Uncoupling protein 1 (Ucp1), PRD1-BF1-RIZ1 homologous domain containing 16 (Prdm16), peroxisome proliferator-activated receptor-γ coactivator 1-α (Pgc-1α), type 2 iodothyronine deiondinase (Dio2), cell death-inducing DNA fragmentation factor, alpha subunit-like effector A (Cidea), elongation of very long chain fatty acid 3 (Elovl3).

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