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Table 1 Calculation for the mass adjustments for equalisation of fibre number in vivo

From: Use of silver nanowires to determine thresholds for fibre length-dependent pulmonary inflammation and inhibition of macrophage migration in vitro

Particle

Calculation to equalise for the same fibre number

Dose (μg/mouse)

Total fibre number

SFA

Short fibre control

10.7

50.48*106

AgNW 3

3/14 × 50

10.7

32.71*106

AgNW 5

5/14 × 50

17.9

31.19 *106

AgNW 10

10/14 × 50

35.7

28.17 *106

AgNW 14

standard

50.0

32.76 *106

LFA*

Long fibre control

50.0

8.24*106

  1. *LFA fibre counting 164,705 fibres/μg on the basis of WHO counting criteria.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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