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Figure 4 | Particle and Fibre Toxicology

Figure 4

From: Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver

Figure 4

DNA strand breaks (SB) and formamidopyrimidine DNA glycosylase (FPG) sensitive sites in lung of CBNP exposed mice. SB (A) and FPG sensitive sites (B) per 106 base pairs in C57BL/6 mouse lung tissue following exposure to 0.000, 0.018, 0.054 or 0.162 mg Printex 90 CBNPs and sacrificed 1, 3, and 28 days post-exposure. Error bars represent the standard error of the mean for 6 mice in each group. *, ** refers to a statistical significance of P < 0.05 and P < 0.001 respectively, when compared by two-factor ANOVA using the day of sacrifice and dose as categorical variables.

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