Figure 4From: Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver DNA strand breaks (SB) and formamidopyrimidine DNA glycosylase (FPG) sensitive sites in lung of CBNP exposed mice. SB (A) and FPG sensitive sites (B) per 106 base pairs in C57BL/6 mouse lung tissue following exposure to 0.000, 0.018, 0.054 or 0.162 mg Printex 90 CBNPs and sacrificed 1, 3, and 28 days post-exposure. Error bars represent the standard error of the mean for 6 mice in each group. *, ** refers to a statistical significance of P < 0.05 and P < 0.001 respectively, when compared by two-factor ANOVA using the day of sacrifice and dose as categorical variables.Back to article page