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Table 2 Expression of Saa3 presented as fold-changes over matched control in C57BL/6 mice 1, 3 and 28 days post-exposure to 0.018, 0.054 and 0.162 mg Printex 90 CBNPs. *, ** refers to a statistical significance of P < 0.05 and P < 0.001 respectively.

From: Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver

  

0.018 mg

0.054 mg

0.162 mg

Lung

    
 

24 h

63.7 ± 33.2 **

240.3 ± 75.4 **

298.2 ± 78.0 **

 

3 days

8.2 ± 4.2 **

23.5 ± 6.7 **

50.5 ± 14.6 **

 

28 days

1.1 ± 0.4

4.9 ± 2.2 **

21.8 ± 10.1 **

Liver

    
 

24 h

1.2 ± 0.5

1.6 ± 0.5

1.3 ± 0.3

 

3 days

0.7 ± 0.2

0.7 ± 0.2

0.7 ± 0.2

 

28 days

1.0 ± 0.2

1.5 ± 0.2

1.3 ± 0.2

  1. n = 6 except for the control groups
  2. (n = 22)