The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells

Table 1 Summary of cytokine release from cells

	IL-1β		IL-6		IL-8		TNFα
	NT _short	NT _long2	NT _short	NT _long2	NT _short	NT _long2	NT _short	NT _long2
Mesothelial cells (pg/m)	205 ± 26	153 ± 17	340 ± 11	347 + 2	392 ± 15	458 ± 16	15 ± 2	10 ± 3
Macrophages (pg/ml)	296 ± 23	506 ± 34	128 ± 39	380 + 8	286 ± 8	403 ± 4	6 ± 2	350 ± 200
Mesothelial cells + conditioned media (pg/ml)	293 ± 2	1012 ± 59	214 ± 8	8479 + 3640	121 ± 29	12130 ± 2254	14 ± 4	2029 ± 328

The cytokine release for the three treatment groups are compared side by side using one short CNT (NT_short) and one long CNT (NT_long2) as exemplars

ISSN: 1743-8977