Table 2 Baseline heart rate, arterial pressure and hind-limb blood flow 6 and 24 h after instillation of diesel exhaust particulate (DEP) or saline (assessed before vasodilator administration)

6 h

24 h

Non-instilled

Saline

DEP

Saline

DEP

HR

(bpm)

354 ± 6

352 ± 7

372 ± 11

335 ± 6

353 ± 7

SBP

(mmHg)

103.9 ± 5.7

105.1 ± 5.1

130.7 ± 13.4*

101.3 ± 2.4

116.9 ± 5.9

DBP

(mmHg)

88.9 ± 6.5

98.7 ± 5.0

122.5 ± 12.8

85.3 ± 2.2

101.8 ± 7.1

MABP

(mmHg)

91.4 ± 7.4

100.9 ± 5.0

125.3 ± 13.0

91.2 ± 1.8

106.8 ± 6.5

HBF

(ml/min)

2.3 ± 0.3

2.4 ± 0.4

2.7 ± 0.2

2.0 ± 0.3

2.6 ± 0.3