Figure 4

Effect of MMA-SS welding fume instillation on protein production of challenged leukocytes. Anticoagulated whole blood was collected 24 h post-instillation to PBS or MMA-SS and challenged with LPS (100 ng/ml). Supernatants were collected 24 h after LPS challenge and assayed for protein concentrations. Data are represented as (concentration)/(leukocytes/ml) times a factor of 10 to obtain a whole number. CXCL10 – pg/leukocyte* 100,000; CCL4 – pg/leukocyte* 10,000; CXCL2 – pg/leukocyte* 1,000,000; TNFα – ng/leukocyte* 100,000,000. *p < 0.05 vs PBS.