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Figure 5 | Particle and Fibre Toxicology

Figure 5

From: Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines

Figure 5

ToxTracker induction by non-metal nanoparticles. (A) The ToxTracker mES cells were exposed to quartz, multi-walled carbon nanotubes and diesel exhaust particles (6.25 – 100 μg/mL) for 24 h. GFP induction and cell viability were determined with flow cytometry. Results are presented as mean ± standard deviation of three independent experiments. (B) The ToxTracker mES cells were exposed to diesel exhaust particles in the presence of S9 rat liver extract for 3 h. GFP induction was determined after 24 h by flow cytometry. Results are presented as mean ± standard deviation of three independent experiments. Aflatoxin B1 was used as a positive control.

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