Table 2 The ability of NPs and their corresponding metal ions to induce the ToxTracker reporters
μg/mL | μM | μg metal/mL | ToxTracker induction | μg released metal/mL in cell medium | Is the released metal in cell medium likely to induce ToxTracker? | |
|---|---|---|---|---|---|---|
CuO NPs | 20 | - | 15,8 | Yes | 7,4 | YES → ionic effect |
CuSO 4 | - | 50 | 3,2 | Yes | - | |
NiO NPs | 20 | - | 15,6 | Yes | 1 | NO → particle effect |
NiCl 2 | - | 250 | 14,7 | No | - | |
ZnO NPs | 20 | - | 16,1 | Yes (↑Tox) | 15,7 | Inconclusive due to high cytotoxicity |
ZnSO 4 | - | 500 | 32,7 | Yes (↑Tox) | - |