Figure 10
Cell count and differentials 4 and 24 h following TiO 2 nanobelt instillations in C57BL/6 wild-type mice and IL-1R null mice (24 hr only). A) Mean ± SEM neutrophil count at 4 and 24 h in WT mice only. B) Mean ± SEM total cell count at 24 h. C) Mean ± SEM alveolar macrophage count at 24 h. D) Mean ± SEM neutrophil count at 24 h. Asterisks indicate significance at ***P < 0.001, **P < 0.01 or *P < 0.05 compared to corresponding dispersion media vehicle (DM). Daggers indicate significance at ††† P < 0.001, †† P < 0.01, or † P < 0.05 compared to corresponding IL-1R particle exposure condition.