Figure 5

Fecal and urinary excretion of⁶⁵Zn post-IT instillation of⁶⁵ZnO and SiO ₂ -coated⁶⁵ZnO NPs. Data are estimated cumulative urinary or fecal excretion of ⁶⁵Zn over 28 days. The predominant excretion pathway was via the feces. Approximately half of the instilled ⁶⁵Zn was excreted in the feces in both groups over 28 days (A). Only about 1% of the ⁶⁵Zn dose was excreted in the urine (B).