Figure 9From: Comparative iron oxide nanoparticle cellular dosimetry and response in mice by the inhalation and liquid cell culture exposure routesSPIO nanoparticle induced gene expression in vitro. Top) A dose dependent increase in gene expression was observed in BMM cells treated with 44-2 carboxy-modified SPIO nanoparticles for 4h. Significance values calculated using Student’s t- test. # < 0.01; Bottom) dose dependent increase in gene expression was observed in C10 cells treated with 44-2 carboxy-modified SPIO nanoparticles for 4 h. Significance values calculated using Student’s t- test. * < 0.05, # < 0.01.Back to article page