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Table 1 Oxidative stress in testis of male mice caused by intragastric administration with TiO 2 NPs for 90 consecutive days

From: RETRACTED ARTICLE: Mechanisms of nanosized titanium dioxide-induced testicular oxidative stress and apoptosis in male mice

Oxidative stress

TiO 2 NPs (mg/kg BW)

0

2.5

5

10

O2 .- (nmol/mg protâ‹…min)

45 ± 2.42

57 ± 2.96*

78 ± 4.28**

103 ± 5.29***

H2O2 (nmol/mg protâ‹…min)

63 ± 3.49

73 ± 3.82*

95 ± 4.86**

125 ± 6.36***

MDA (nmol/ mg prot)

570 ± 29.62

1030 ± 51.72*

1880 ± 95.08**

2580 ± 130.55***

PC (nmol/mg prot)

960 ± 48.75

1170 ± 58.93*

2220 ± 112.56**

4070 ± 205.57***

8-OHdG (ng/g tissue)

310 ± 15.86

3390 ± 169.78*

6380 ± 320.81**

8660 ± 435.63***

  1. *p < 0.05, **p < 0.01, and ***p < 0.001. Values represent mean ± SD (N = 5).