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Table 1 Oxidative stress in testis of male mice caused by intragastric administration with TiO 2 NPs for 90 consecutive days

From: RETRACTED ARTICLE: Mechanisms of nanosized titanium dioxide-induced testicular oxidative stress and apoptosis in male mice

Oxidative stress TiO 2 NPs (mg/kg BW)
0 2.5 5 10
O2 .- (nmol/mg protmin) 45 ± 2.42 57 ± 2.96* 78 ± 4.28** 103 ± 5.29***
H2O2 (nmol/mg protmin) 63 ± 3.49 73 ± 3.82* 95 ± 4.86** 125 ± 6.36***
MDA (nmol/ mg prot) 570 ± 29.62 1030 ± 51.72* 1880 ± 95.08** 2580 ± 130.55***
PC (nmol/mg prot) 960 ± 48.75 1170 ± 58.93* 2220 ± 112.56** 4070 ± 205.57***
8-OHdG (ng/g tissue) 310 ± 15.86 3390 ± 169.78* 6380 ± 320.81** 8660 ± 435.63***
  1. *p < 0.05, **p < 0.01, and ***p < 0.001. Values represent mean ± SD (N = 5).