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Table 2 Alterations of antioxidative capacity in mouse testis after intragastric administration with TiO 2 NPs for 90 consecutive days

From: RETRACTED ARTICLE: Mechanisms of nanosized titanium dioxide-induced testicular oxidative stress and apoptosis in male mice

Enzyme activity

TiO 2 NPs (mg/kg BW)

0

2.5

5

10

SOD (unit/mg proteinâ‹…min)

51 ± 2.71

35 ± 1.79*

23 ± 1.39**

13 ± 0.72***

CAT (unit/mg proteinâ‹…min)

73 ± 3.82

53 ± 2.79*

35 ± 1.86**

25 ± 1.39***

GSH-Px (unit/mg proteinâ‹…min)

57 ± 2.96

43 ± 2.29*

29 ± 1.56**

18 ± 1.15***

GST (unit/mg proteinâ‹…min)

50 ± 2.65

37 ± 2.06*

22 ± 1.2**

15 ± 0.8***

GR (unit/mg proteinâ‹…min)

59 ± 3.23

50 ± 2.65*

36 ± 1.85**

29 ± 1.56***

GSH (ng/g tissue)

2360 ± 118.56

1910 ± 95.53*

1090 ± 55.56**

510 ± 25.68***

Ascorbic acid (ng/g tissue)

2050 ± 103.28

1480 ± 75.22*

850 ± 43.55**

420 ± 22.67***

  1. *p < 0.05, **p < 0.01, and ***p < 0.001. Values represent mean ± SD (n = 5).