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Figure 2 | Particle and Fibre Toxicology

Figure 2

From: Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation

Figure 2

Ag NWs increase total BALF cells and protein. Graphs show absolute numbers of total cells (left), and proteins (right) in BALF on Days 1-21 post IT of S-Ag NWs (A-B), or L-Ag NWs (C-D). Results are from ANOVA considering dose, time, and particle length at p < 0.05. “D” corresponds specifically to differences between groups (in the same panel, sacrificed on the same day) given 1.0 mg/kg Ag NWs versus any other dose; while, “d” indicates differences from the sham control and 0.01 mg/kg groups only. “T” indicates differences between animals (in the same panel, given the same treatment) sacrificed on Day 1 versus Days 7 and 21; while, “T” indicates difference from Day 21 only. “A” indicates a significant difference between groups (in different panels) given the same dose of different Ag NW types (e.g. S- versus L-Ag NWs), but sacrificed on the same day.

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