TY - JOUR AU - Liu, Cuiqing AU - Fonken, Laura K. AU - Wang, Aixia AU - Maiseyeu, Andrei AU - Bai, Yuntao AU - Wang, Tse-Yao AU - Maurya, Santosh AU - Ko, Yi-An AU - Periasamy, Muthu AU - Dvonch, Timothy AU - Morishita, Masako AU - Brook, Robert D. AU - Harkema, Jack AU - Ying, Zhekang AU - Mukherjee, Bhramar AU - Sun, Qinghua AU - Nelson, Randy J. AU - Rajagopalan, Sanjay PY - 2014 DA - 2014/10/30 TI - Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes JO - Particle and Fibre Toxicology SP - 53 VL - 11 IS - 1 AB - Prior experimental and epidemiologic data support a link between exposure to fine ambient particulate matter (<2.5 μm in aerodynamic diameter, PM2.5) and development of insulin resistance/Type II diabetes mellitus (Type II DM). We investigated the role of hypothalamic inflammation in PM2.5-mediated diabetes development. SN - 1743-8977 UR - https://doi.org/10.1186/s12989-014-0053-5 DO - 10.1186/s12989-014-0053-5 ID - Liu2014 ER -