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Figure 5 | Particle and Fibre Toxicology

Figure 5

From: Ozone co-exposure modifies cardiac responses to fine and ultrafine ambient particulate matter in mice: concordance of electrocardiogram and mechanical responses

Figure 5

Effect of CAPs exposure with and without O 3 on rate of left ventricle contractility and relaxation. Assessment of contractility (dP/dtmax - upper panel) and lusitropy (dP/dtmin - lower panel) were carried out at baseline 24 hrs after exposure - prior to ischemia. Exposure to FCAPs alone significantly decreased dP/dtmax and dP/dtmin at baseline when compared to FA, however there was no effect with O3 co-exposure (FCAPs/O3). In contrast, UFCAPs alone had no effect; but, O3 co-exposure with UFCAPs (UFCAPs/O3) caused both dP/dtmax and dP/dtmin to significantly decrease when compared to FA. Values are means ± SEM (n = 5-8 in each group). *Significantly different from FA; p < 0.05.

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Particle and Fibre Toxicology

ISSN: 1743-8977

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