Clearance and translocation of131BaSO
NPs following IT instillation. (A) Lung clearance of 131BaSO4 over time. The clearance half life was approximately 9.6 days. By 28 days, 84% of dose has been cleared from the lungs. (B) Translocated 131Ba from the lungs gradually accumulated in other organs. By 28 days, 29% of the instilled 131Ba dose was retained in the bone and 7% in all the other organs. Data are mean ± standard error of the mean, n = 5 per group.